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The American journal Epilepsy & Behavior recently published an analysis of the health status of 75 children who took cannabis inflorescence extract orally to treat epilepsy. The analysis was conducted by researchers from the Children's Hospital in Denver, Colorado in the USA.
The authors report that the health of 58% of patients improved, the number of attacks on a weekly basis decreased, and almost 33% of them managed to reduce it by more than half. Doctors also report that in the same group of children, focus improved and 10% also had an improvement in physical performance.
Side effects appeared in 44% of the subjects, of which 13% began to experience increased attacks, and 12% felt drowsy. The authors, however, also state that extracts from cannabis inflorescences are tolerated well by children, because drastic side effects, requiring medical intervention, occurred very rarely.
Another clinical trial report was presented a week earlier by the Academy of Neurology. We can read in it that an orally taken extract containing CBD (e.g. cbd oil) reduced the incidence of attacks in patients with epilepsy by 54% during the 12-week treatment period.
The study included a group of 213 patients of different ages who had not previously responded to any form of treatment. Among them were patients with Dravet syndrome, Lennox-Gastault syndrome and other varieties of severe epilepsy. The subjects took an extract containing CBD-cbd oil (a non-psychoactive compound contained in marijuana) orally daily and were aware of what they were taking, but the study was primarily aimed at determining whether the agent is primarily well tolerated by the body.
After completing the treatment, 137 subjects had a 54% reduction in the number of attacks. Only 12 of the patients or 6% had to stop taking the extract due to side effects that occurred in a total of only 10% of patients. Those complained of drowsiness or lack of energy (21%), diarrhea (17%), fatigue (17%), and loss of appetite (16%).
The study's author, Dr. Orrin Devinsky of New York University's Langone Comprehensive Epilepsy Center and a member of the American Academy of Neurology, said these are very early conclusions and that more detailed, double-blind studies should be conducted to confirm the effectiveness of the drug. However, he confirmed that "the results are very interesting and promising."
Source: American Academy of Neurology / Epilepsy & Behavior